CRMetrics - Cell Ranger Output Filtering and Metrics Visualization
Sample and cell filtering as well as visualisation of
output metrics from 'Cell Ranger' by Grace X.Y. Zheng et al.
(2017) <doi:10.1038/ncomms14049>. 'CRMetrics' allows for easy
plotting of output metrics across multiple samples as well as
comparative plots including statistical assessments of these.
'CRMetrics' allows for easy removal of ambient RNA using
'SoupX' by Matthew D Young and Sam Behjati (2020)
<doi:10.1093/gigascience/giaa151> or 'CellBender' by Stephen J
Fleming et al. (2022) <doi:10.1101/791699>. Furthermore, it is
possible to preprocess data using 'Pagoda2' by Nikolas Barkas
et al. (2021) <https://github.com/kharchenkolab/pagoda2> or
'Seurat' by Yuhan Hao et al. (2021)
<doi:10.1016/j.cell.2021.04.048> followed by embedding of cells
using 'Conos' by Nikolas Barkas et al. (2019)
<doi:10.1038/s41592-019-0466-z>. Finally, doublets can be
detected using 'scrublet' by Samuel L. Wolock et al. (2019)
<doi:10.1016/j.cels.2018.11.005> or 'DoubletDetection' by
Gayoso et al. (2020) <doi:10.5281/zenodo.2678041>. In the end,
cells are filtered based on user input for use in downstream
applications.